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Spatial statistics infer structured immune signatures in primary prostate cancer.

Ali Amiryousefi, Jeremiah Wala, Jia-Ren Lin, Brian William Labadie, Aishwarya Atmakuri, Zoltan Maliga, Eamon Toye, Kiranj Chaudagar, Madeleine S Torcasso, Shannon Coy, Giuseppe Nicolo Fanelli, Brigette Kobs, Fabio Socciarelli, Andréanne Gagné, Eliezer M Van Allen, Akash Patnaik, Peter Sorger

Cancer immunology researchSep 11, 2026PMID 42726512doi:10.1158/2326-6066.CIR-26-0106 Journal ArticlepubmedProvenance
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PubMed
Retrieved
Sep 13, 2026
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normalized (units and labels harmonized; values unchanged)
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ING-PUBMED-20260913-000001
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The spatial arrangement of immune cells in the tumor microenvironment (TME) varies widely, from dispersed to clustered and tumor excluded to infiltrating. Multiplexed spatial profiling is an effective means of characterizing tumor-infiltrating lymphocytes (TILs) and immune complexes such as…

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