Publication
Nutrient deprivation enhances the cytotoxic effects of a sulfonamide-chalcone hybrid in PC-3 prostate cancer cells.
Gisele Santos de Araújo, Rodrigo Elísio de Sá, Stéphanie Aguiar de Negreiros Matos Silva, Fabrício Dos Santos Machado, Caridad Noda Perez, Mirian Rita Carrilho de Castro, Anali Del Milagro Bernabe Garnique, Bruna Oliveira de Almeida, Keli Lima, João Agostinho Machado Neto, Letícia Veras Costa Lotufo, José Delano Barreto Marinho Filho, Ana Jérsia Araujo
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- PubMed
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- Sep 13, 2026
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- normalized (units and labels harmonized; values unchanged)
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- ING-PUBMED-20260913-000001
Abstract
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Hybrid molecules integrating different pharmacophoric motifs have emerged as a promising strategy in anticancer drug discovery. In this study, we report for the first time the biological effects of a sulfonamide-chalcone hybrid in the PC-3 prostate cancer cell line under standard culture conditions…
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- cancerMalignant Prostate Neoplasmdictionary0.60
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