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SFRP2 Potentiates Metastasis of Colon Cancer by Enhancing Snai1 Protein Stability via USP11.

Yanshen Kuang, Xin Liu, Mu Ke, Zhijie Chang, Baoqing Jia, Bing Li, Honggang Qian

Journal of cellular and molecular medicineSep 1, 2026PMID 42725854doi:10.1111/jcmm.71318 PMC13564241Journal ArticlepubmedProvenance
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PubMed
Retrieved
Sep 16, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260916-000001
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Metastatic colon cancer remains a significant clinical challenge, often associated with poor patient prognosis. Recent studies have identified the secreted frizzled-related protein 2 (SFRP2) as a key player in this malignancy, showing its overexpression in metastatic cases. This research aimed to…

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