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Multifunctional Nanovaccine-Radiotherapy Synergy Drives Anti-Tumor Immunity via Multi-Cascade Cell Death for Pancreatic Cancer Therapy.

Chengyi Huang, Yushu Han, Xiang Liu, Chuanhao Wang, Xiaofei Zhu, Di Chen, Yangyang Gong, Liang Chen, Wenjuan Chen, Zhenyuan Miao, Bufu Tang, Huojun Zhang

Advanced science (Weinheim, Baden-Wurttemberg, Germany)Sep 10, 2026PMID 42723174doi:10.1002/advs.77651 PMC13562777Journal ArticlepubmedProvenance
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PubMed
Retrieved
Sep 15, 2026
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normalized (units and labels harmonized; values unchanged)
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ING-PUBMED-20260915-000001
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Pancreatic adenocarcinoma (PAAD) is an immunosuppressive malignancy refractory to radiotherapy and immunotherapy. Conventional tumor vaccines fail in PAAD due to a suppressive tumor microenvironment (TME), inadequate antigen presentation, and impaired immunogenic cell death (ICD). Using a machine…

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