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Baseline serum carcinoembryonic antigen (CEA) is an independent prognostic biomarker for metastatic castration-resistant prostate cancer (mCRPC) patients receiving 177Lu-PSMA therapy.

Emilio Francesco Giunta, Irene Marini, Ilaria Grassi, Silvia Nicolini, Flavia Foca, Monica Celli, Paola Caroli, Anna Sarnelli, Nicole Brighi, Giuseppe Schepisi, Manuela Monti, Ugo De Giorgi, Cristian Lolli, Maddalena Sansovini

European journal of nuclear medicine and molecular imagingSep 11, 2026PMID 42722919doi:10.1007/s00259-026-08173-x Journal ArticlepubmedProvenance
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PubMed
Retrieved
Sep 13, 2026
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normalized (units and labels harmonized; values unchanged)
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ING-PUBMED-20260913-000001
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PURPOSE: 177Lu-PSMA is currently approved for metastatic castration-resistant prostate cancer (mCRPC). However, only a subset of eligible patients derives a meaningful clinical benefit from treatment. To date, there is a lack of validated biomarkers that could help find the best candidates for this…

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