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Early versus late closure of protective ileostomy after rectal cancer surgery.

Elias Khajeh, Andrea Sosková, Johanna Fellhofer-Hofer, Nastaran Sabetkish, Rajan Nikbakhsh, Mohammadamin Shahrbaf, Arianeb Mehrabi, Fee Klupp

International journal of colorectal diseaseSep 10, 2026PMID 42722914doi:10.1007/s00384-026-05239-y PMC13562142Journal ArticleMeta-AnalysisSystematic ReviewComparative StudypubmedProvenance
Source
PubMed
Retrieved
Sep 19, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260919-000001
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PURPOSE: The optimal timing of protective ileostomy closure after rectal cancer surgery remains uncertain. This systematic review and meta-analysis compares early (EC) versus late closure (LC) and evaluates the associated risks and benefits. METHODS: Medline, Web of Science, and CENTRAL were…

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