Publication
Trigonelline reverses cisplatin resistance in ovarian cancer cells by modulating ferroptosis via the Nrf2/GPX4 pathway.
Jing Li, Xiaoxiao Wang, Liya Tu, Yufeng Chen
Toxicon : official journal of the International Society on ToxinologySep 10, 2026PMID 42722238doi:10.1016/j.toxicon.2026.109304 Journal ArticlepubmedProvenance
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- Sep 16, 2026
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Ovarian cancer (OC) exhibits the highest mortality rate among gynecological cancers, and the development of chemotherapy resistance serves as the primary cause of patient recurrence and death. Natural products hold promise in reversing cisplatin (DDP) resistance. Trigonelline is a natural alkaloid…
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- cancerMalignant Ovarian Neoplasmdictionary0.60
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