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Targeting lipid metabolism-associated lncHMGCS1 suppressed cell proliferation and restored intracellular lipid homeostasis by regulating ACSL3 in gastric cancer.

Qiang Yang, Yuyang He, Lejia Wang, Xiaoxia Yuan, Jingping Zhang, Jinxin Chen, Guohui Jiang, Wenrong Ma, Xingtong Lu, Chen Wei, Bin Zhang, Shihao Deng, Yaomin Luo, Yang Xiao, Kexun Long, Chaoying Xu, Xinqiang Yin, Zhen Jiang

European journal of pharmacologySep 10, 2026PMID 42722057doi:10.1016/j.ejphar.2026.179339 Journal ArticlepubmedProvenance
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PubMed
Retrieved
Sep 15, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260915-000001
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Previous work has indicated that lipid metabolic reprogramming plays a critical role in gastric cancer (GC) development, yet the underlying molecular mechanisms remain largely undefined. In the present study, we identified a novel lipid metabolism-associated long non-coding RNA,…

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