Publication
NeoGen-BC: A synergistic framework combining generative protein language models and multi-window deep learning for designing shared neoantigens in breast cancer.
Van The Le, Juan Peter Timothy Yuune, Jiun-I Lai, Yu-Yen Ou
Biochemical and biophysical research communicationsOct 22, 2026PMID 42721858doi:10.1016/j.bbrc.2026.154567 Journal ArticlepubmedProvenance
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- Oct 2, 2026
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- ING-PUBMED-20261002-000001
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Breast cancer, particularly hormone receptor-positive (HR+) and triple-negative (TNBC) subtypes, is often immunologically "cold," limiting immunotherapy efficacy. Neoantigen-based vaccines hold promise but face challenges from inaccurate identification and overreliance on HLA binding affinity,…
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- cancerMalignant Breast Neoplasmdictionary0.60
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