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An Atlas of Specificity Protein 1 in Oral Cancer: Networks, Therapeutics, and Priorities: A Scoping Review and scRNA-seq Analysis.

Su-Jung Choi, Neeti Swarup, Seong-Doo Hong, Thantrira Porntaveetus, Sung-Dae Cho

International dental journalSep 10, 2026PMID 42721688doi:10.1016/j.identj.2026.111141 Journal ArticleReviewpubmedProvenance
Source
PubMed
Retrieved
Sep 30, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260930-000001
Published

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Oral squamous cell carcinoma (OSCC) remains the most common oral malignancy and has limited targeted therapeutic options. Specificity protein 1 (Sp1), a versatile zinc-finger transcription factor, has emerged as a pivotal regulator of cellular proliferation, apoptosis, epithelial-mesenchymal…

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