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Response to alemtuzumab-based therapy and long-term survival after allogeneic transplantation in T-Cell prolymphocytic leukemia: a systematic review and meta-analysis of proportions.

Jamiel Reyes, Alexander Reyes

European journal of clinical pharmacologySep 10, 2026PMID 42720768doi:10.1007/s00228-026-04182-9 Journal ArticleSystematic ReviewMeta-AnalysispubmedProvenance
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PubMed
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Sep 19, 2026
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normalized (units and labels harmonized; values unchanged)
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ING-PUBMED-20260919-000001
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INTRODUCTION: T-cell prolymphocytic leukemia (T-PLL) is a rare, aggressive neoplasm with poor outcomes. Alemtuzumab and allogeneic hematopoietic cell transplantation (allo-HCT) are the mainstays of treatment, yet estimates rest on small single-arm studies, and no synthesis has pooled both outcomes.…

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