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Interpretable four-class machine learning prediction of initial I-131 therapy responses in differentiated thyroid cancer.

Yangyang Lei, Yi Mao, Rui Zhu, Zhaoxia Luo, Qing Zhang

Annals of medicineDec 1, 2026PMID 42720506doi:10.1080/07853890.2026.2729596 PMC13564170Journal ArticleResearch Support, Non-U.S. Gov'tpubmedProvenance
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PubMed
Retrieved
Sep 29, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260929-000001
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BACKGROUND: Differentiated thyroid carcinoma (DTC) responses to initial post-operative I-131 therapy are heterogeneous. Standard binary models combine incomplete responses into a 'non-excellent' category, obscuring transitional states (indeterminate response [IDR] and biochemical incomplete…

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