Publication
A 177Lu-Labeled Circular Bivalent Aptamer for PTK7-Targeting Radionuclide Therapy in Ovarian Cancer and Orthotopic Hepatoblastoma.
Xiaoning Tong, Yi He, Heng Liu, Wenjie Guo, Wen-Guo Huang, Peng Li, Luoan Wang, Yuntian Zhu, Le Cai, He-Qing Yi, Xue-Qiang Wang, Weihong Tan
- Source
- PubMed
- Retrieved
- Sep 16, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-PUBMED-20260916-000001
Abstract
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Targeted radionuclide therapy (TRT) is a promising strategy for precision oncology but is limited by the lack of high-performance targeting ligands. Here, we report a lutetium-177 (177Lu)-labeled PTK7-targeted cyclized bivalent aptamer (CBSgc8) for treating an orthotopic hepatoblastoma. The…
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- cancerMalignant Ovarian Neoplasmdictionary0.60
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