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ENCERT: A Multisite Phase 1 Trial Using Everolimus in Combination With Nelarabine, Cyclophosphamide, and Etoposide in Relapsed T-Cell Lymphoblastic Leukemia/Lymphoma.

Himalee S Sabnis, Melinda Pauly, Eric S Schafer, Robin E Norris, Kevin Ginn, Tsz Yeung, Naresh Kumar, Stacy Senn, Haley Cowan, Deborah DeRyckere, Christopher J Forlenza, Neerav Shukla

Pediatric blood & cancerNov 1, 2026PMID 42720434doi:10.1002/1545-5017.70662 Journal ArticleMulticenter StudyClinical Trial, Phase IpubmedProvenance
Source
PubMed
Retrieved
Sep 29, 2026
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normalized (units and labels harmonized; values unchanged)
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ING-PUBMED-20260929-000001
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BACKGROUND: Relapsed and refractory (R/R) T-cell acute lymphoblastic leukemia/lymphoma (T-ALL/T-LL) remains a therapeutic challenge. Allogeneic hematopoietic stem cell transplantation (HSCT) after achieving complete remission (CR) offers the only chance of cure, but effective modalities to achieve…

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Registered trialsNCT03328104

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