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Target Antigen Identification for Antibody Drug Conjugate Therapy in Biliary Tract Cancer.

Aruj Dhyani, Nuray Tezcan, Joanne F Chou, Zeynep Tarcan, Rohit Thummalapalli, Fatema Nagib, Orla M Fitzpatrick, Darren Cowzer, Danny N Khalil, Wungki Park, Lily V Saadat, Kevin Soares, Alice Wei, William Jarnagin, Nikolaus Schultz, Joseph P Erinjeri, Mark Dunphy, David Solit, Walid Chatila, Eileen M O'Reilly, Ghassan K Abou-Alfa, Marinela Capanu, Olca Basturk, James J Harding

Clinical cancer research : an official journal of the American Association for Cancer ResearchSep 10, 2026PMID 42720429doi:10.1158/1078-0432.CCR-26-1720 Journal ArticlepubmedProvenance
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PubMed
Retrieved
Sep 30, 2026
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normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260930-000001
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BACKGROUND: Data on antibody-drug conjugates (ADCs) target expression prevalence, intertumoral heterogeneity, genomic concordance, and its effect on clinical outcomes is limited in biliary tract cancers (BTC). METHODS: Resected primary BTC specimens, and when available, matched metastatic samples…

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Registered trialsNCT01775072

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