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Bacteria-Based Ammunition for Cascade-Amplified Chemoimmunotherapy of Ovarian Cancer.

Zhuorong Miao, Yafang Lu, Yu Zhang, Xinghui Si, Zhen Wu, Huaibin Yu, Ping Jin, Zhengbao Zha

Nano lettersSep 9, 2026PMID 42715039doi:10.1021/acs.nanolett.6c02787 Journal ArticleResearch Support, Non-U.S. Gov'tpubmedProvenance
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PubMed
Retrieved
Sep 15, 2026
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normalized (units and labels harmonized; values unchanged)
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ING-PUBMED-20260915-000001
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Ovarian cancer is the deadliest gynecological malignancy due to poor drug targeting, severe toxicity, and an immunosuppressive tumor microenvironment (TME). To address this, a pH/GSH dual-responsive bacterial-nanoparticle system (VNP@BD-Poly) based on attenuated Salmonella VNP20009 (VNP) was…

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