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Deubiquitination of NICD1 by USP10 Restrains Esophageal Cancer: A Link Between NOTCH1 Stabilization, Oxidative Stress, and Ferroptosis.

Xiufeng Tang, Zhiqin Zhang, Xinyi Wei, Yanshuang Yang, Zongxin Shi, Haonan Fan, Minxuan Xu, Chengxin Liu

Neoplasia (New York, N.Y.)Sep 8, 2026PMID 42710266doi:10.1016/j.neo.2026.101358 PMC13573680Journal ArticlepubmedProvenance
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PubMed
Retrieved
Sep 19, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260919-000001
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The development of new drugs and focused treatment strategies is significantly hampered by the inadequate understanding of the complex pathophysiology of esophageal cancer (EC). Significant risk factors for the development of EC include imbalances in the oxidative stress and anti-oxidative response…

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