Publication
From cell counts to cellular interactions: Cu-Cyto and the co-localization index as a spatial framework for the tumor immune microenvironment of rectal cancer.
Kimihiro Yamashita, Toru Nagasaka, Tomoki Abe, Yukari Adachi, Ryota Ito, Takaaki Tachibana, Toru Takahashi, Hiroki Kagiyama, Masaki Imai, Takao Tsuneki, Masayuki Ando, Yuna Asano, Kumiko Miyashita, Yasunori Otowa, Naoki Urakawa, Hironobu Goto, Hiroshi Hasegawa, Shingo Kanaji, Mitsugu Fujita, Takeru Matsuda, Ryohei Sasaki, Takumi Fukumoto, Yoshihiro Kakeji
- Source
- PubMed
- Retrieved
- Sep 18, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-PUBMED-20260918-000001
Abstract
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The tumor immune microenvironment in colorectal cancer has emerged as a major determinant of patient outcome, with tumor-infiltrating lymphocytes, particularly CD8⁺ T cells, mediating antitumor immunity. Standardized density-based metrics such as the Immunoscore have demonstrated prognostic value…
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Candidate 1
- cancerMalignant Rectal Neoplasmdictionary0.60
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