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Navigating Antibody-Drug Conjugate Sequencing in Gastric Cancer: Cross-Resistance Biology, Target Switching, and Decision-Making Frameworks for the Post-Progression Landscape.

Yue Wu

Current oncology reportsSep 8, 2026PMID 42709339doi:10.1007/s11912-026-01826-y Journal ArticleReviewpubmedProvenance
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PubMed
Retrieved
Sep 13, 2026
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normalized (units and labels harmonized; values unchanged)
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ING-PUBMED-20260913-000001
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PURPOSE OF REVIEW: Antibody-drug conjugates (ADCs) have reshaped the therapeutic landscape of advanced gastric cancer, with trastuzumab deruxtecan (T-DXd) and disitamab vedotin (RC48) establishing new standards for HER2-positive disease, and a wave of Claudin 18.2 (CLDN18.2)-directed ADCs…

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