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Transdermal Estradiol for Treating Prostate Cancer: Revisiting Huggins and Hodges' Revolutionary Breakthrough.

David J Benjamin, Arash Rezazadeh Kalebasty

European urology oncologySep 7, 2026PMID 42705946doi:10.1016/j.euo.2026.08.011 EditorialpubmedProvenance
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PubMed
Retrieved
Sep 9, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260909-000004
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Androgen deprivation therapy remains the cornerstone of treating prostate cancer and is now available in multiple formulations based on several randomized phase 3 trials. The estradiol patch offers numerous potential advantages, including fewer hot flashes, less adverse impact on bone health, and…

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