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SMPDM3B-loaded extracellular vesicles from tumor-associated macrophages drive ovarian cancer chemoresistance by inhibiting the cGAS/STING pathway.

Xin Liang, Hanlu Yang, Lan Hong

Archives of biochemistry and biophysicsSep 7, 2026PMID 42705430doi:10.1016/j.abb.2026.110995 Journal ArticlepubmedProvenance
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PubMed
Retrieved
Sep 14, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260914-000001
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Tumor-associated macrophages (TAMs) are implicated in the enhanced chemoresistance of ovarian cancer (OC), with extracellular vesicles (EVs) serving as important mechanism mediating intercellular communication. This study aimed to investigate the role of TAMs-derived EVs in OC chemoresistance.…

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