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PRDX1 facilitates USP7-dependent stabilization of SCD1 and promotes bladder cancer progression.

Li Wang, Jianwei Yang, Shun Wan, Kunpeng Li, Panpan Jiao, Yidi Deng, Hanlin Liu, Siyu Chen, Xiaoqiang Si, Li Yang

Cellular signallingSep 7, 2026PMID 42705398doi:10.1016/j.cellsig.2026.112882 Journal ArticlepubmedProvenance
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PubMed
Retrieved
Sep 17, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260917-000001
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Bladder cancer is characterized by redox adaptation and metabolic plasticity, but the mechanisms linking these processes remain incompletely understood. Integrating bulk, single-cell, and spatial transcriptomic analyses, we identified PRDX1 as a malignant epithelial cell-associated factor linked to…

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