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Dickkopf-1 (DKK1) controls papillary and follicular thyroid cancer growth.

Gloria Fiorentino, Beatrice Latiano, Letizia Rinella, Cristina Grange, Massimo Cedrino, Ornella Bosco, Chiara Pighi, Laura Perin, Emanuela Arvat, Maria Graziella Catalano

Endocrine-related cancerSep 7, 2026PMID 42704709doi:10.1530/ERC-26-0026 Journal ArticlepubmedProvenance
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PubMed
Retrieved
Sep 18, 2026
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normalized (units and labels harmonized; values unchanged)
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ING-PUBMED-20260918-000001
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Thyroid cancer, the most frequent endocrine tumor, has a good prognosis. However, the survival rate of patients with recurrent or metastatic forms that become resistant to conventional treatments, drops to less than 20% at 10 years, with a mean life expectancy of 3-5 years. The molecular mechanisms…

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