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Real-world characteristics of trastuzumab deruxtecan-related interstitial lung disease in Japanese patients with breast cancer and gastric cancer.

Yutaka Fujiwara, Katsunori Oikado, Tomohisa Baba, Masahiko Kusumoto, Shinichi Sasaki, Masahiro Endo, Terufumi Kato, Yasuyuki Kurihara, Yoshinobu Saito, Kunihiro Yagihashi, Masafumi Sata, Yoshinao Sato, Hirotsugu Kenmotsu, Taiki Fukuda, Teppei Yamaguchi, Saiko Isshiki, Hiroshi Wakui, Haruki Kobayashi, Satoshi Ikeda, Motoyasu Kato, Ou Yamaguchi, Toshimi Takano, Ken Kato, Yoshiharu Hiruma, Koji Hirata, Wataru Hashimoto, Kazuyoshi Kuwano

The oncologistSep 7, 2026PMID 42704682doi:10.1093/oncolo/oyag340 Journal ArticlepubmedProvenance
Source
PubMed
Retrieved
Sep 12, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260912-000001
Published

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BACKGROUND: Interstitial lung disease (ILD)/pneumonitis is an important adverse drug reaction associated with trastuzumab deruxtecan (T-DXd). This report comprehensively characterized clinical and imaging features of T-DXd-related ILD, systematically evaluated by an independent ILD Adjudication…

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