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Evidence Gap in Managing Lateral Pelvic Lymph Nodes in Rectal Cancer: a Systematic Review of Radiation Boost Strategies.

Sedat Alp Pinar, Tin-Ning Wong, Timothy Mitchell, Chia Yew Kong

Journal of gastrointestinal cancerSep 7, 2026PMID 42704578doi:10.1007/s12029-026-01580-1 PMC13550032Journal ArticleSystematic ReviewReviewpubmedProvenance
Source
PubMed
Retrieved
Sep 18, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260918-000001
Published

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PURPOSE: Lateral pelvic lymph node (LPLN) involvement is a significant predictor of local recurrence in patients with locally advanced rectal cancer (LARC). While lateral pelvic lymph node dissection (LPLND) is routinely used in some countries to manage suspicious nodes, it is associated with…

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