Skip to content
CancerIndex

Publication

De-escalated total neoadjuvant therapy for the non-operative management of rectal cancer: Results of the NOM-3/TNT prospective cohort study.

Bartłomiej Skrzypiec, Karol Paciorek, Lucyna Pietrzak, Agnieszka Żółciak-Siwińska, Michał F Kaminski, Ewa Wrońska, Anna Hołdakowska, Aleksandra Kapała, Konrad Tałasiewicz, Tomasz Olesiński, Krzysztof Bujko

Clinical and translational radiation oncologyNov 1, 2026PMID 42703503doi:10.1016/j.ctro.2026.101266 PMC13546818Journal ArticlepubmedProvenance
Source
PubMed
Retrieved
Sep 19, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260919-000001
Published

Abstract

Abstract (excerpt)

Only the opening of the abstract is shown; abstract text may carry publisher copyright.

BACKGROUND AND PURPOSE: Total neoadjuvant therapy (TNT) enables non-operative management, although at the cost of increased toxicity. We evaluated a de-escalated TNT-based watch-and-wait (w-w) regimen aimed at reducing toxicity and improving oncological safety through early surgery for…

Read on PubMed

Linked entities

Linked entities (1)

How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.

Candidate 1

Curated evidence

Evidence citing this paper (0)

Data not yet available

No curated evidence item cites this publication.