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Efficacy and Safety of CAR-T Cell Therapy in Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia With Central Nervous System Involvement.

Yanghong Yu, Hui Xu, Lei Xue, Xingbing Wang

Cancer medicineSep 1, 2026PMID 42702862doi:10.1002/cam4.72262 PMC13547739Journal ArticlepubmedProvenance
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PubMed
Retrieved
Sep 9, 2026
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normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260909-000004
Published

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Central nervous system (CNS) involvement in B-cell acute lymphoblastic leukemia (B-ALL) is associated with relapse, treatment refractoriness, and poor prognosis. Although chimeric antigen receptor (CAR) T cell therapy has demonstrated remarkable efficacy in relapsed/refractory (R/R) B-ALL, its…

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