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Single-Cell Transcriptome of Anaplastic Thyroid Cancer Reveals Immunosuppressive Tumor Microenvironment Remodeling.

Saeko Tahara, Akiko Iguchi-Manaka, Naoto Takeuchi, Tomohei Matsuo, Akira Shibuya, Kazuko Shibuya, Haruka Ozaki

Cancer medicineSep 1, 2026PMID 42702761doi:10.1002/cam4.72261 PMC13547591Journal ArticlepubmedProvenance
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PubMed
Retrieved
Sep 15, 2026
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normalized (units and labels harmonized; values unchanged)
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ING-PUBMED-20260915-000001
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Anaplastic thyroid cancer (ATC) is a rare but extremely aggressive malignancy responsible for most thyroid cancer-related deaths. To elucidate molecular and immunological characteristics distinguishing ATC from aggressive papillary thyroid cancer (PTC), we performed single-cell RNA sequencing on…

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