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Acute leukemia therapy at a crossroads: from conventional chemotherapy to the era of precision medicine.

Naoko Hosono, Naoko Ida, Takahiro Yamauchi

Biochemical pharmacologySep 6, 2026PMID 42702241doi:10.1016/j.bcp.2026.118440 Journal ArticleReviewpubmedProvenance
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PubMed
Retrieved
Sep 8, 2026
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normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260908-000002
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Since the discovery of cytotoxic agents in the mid-20th century, acute leukemia has consistently served as a model for oncology research. As the Human Genome Project and subsequent genomic profiling elucidated the landscape of somatic mutations and cytogenetic aberrations driving leukemogenesis,…

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