Publication
A pancreatic cancer organoid-macrophage co-culture using starPEG-heparin hydrogel deciphers tumor-immune cell interactions.
Julius Thyen, Victor A Sioson, Daniel Haak, Beatrix Jahnke, Maximilian Fusenig, Abdul M Aftab, Antonia Stammberger, Sascha Brückmann, Heike Polster, Stefanie Hübner, Verena J Kast, Manuel Pfeifer, Rebecca Prause, Vivian Mittné, Carolin Beer, Malin H Reinhart, Adrian M Seifert, Lena Seifert, Martin Bornhäuser, Carsten Werner, Marc Schmitz, Daniela E Aust, Jürgen Weitz, Daniela Loessner, Daniel E Stange, Anna R Poetsch, Mathieu Pecqueux, Franziska Baenke
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- PubMed
- Retrieved
- Sep 10, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-PUBMED-20260910-000001
Abstract
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Macrophages are among the most abundant immune cells in the pancreatic ductal adenocarcinoma (PDAC) tumor microenvironment (TME) and play a key role in regulating the immunosuppressive niche that facilitates tumor growth. Although recent three-dimensional (3D) culture systems using patient-derived…
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- cancerMalignant Pancreatic Neoplasmdictionary0.60
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