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Anti-angiogenic and anti-metastatic effects of PEDF overexpression in anaplastic thyroid cancer cells: A preliminary in vitro study.

Amineh Khoshnazar, Ameneh Koochaki, Sara Anajafi, Yalda Khazaei-Poul, Hossein Ghanbarian, Samira Mohammadi-Yeganeh, Mahdi Paryan, Vahid Haghpanah

Cancer treatment and research communicationsSep 4, 2026PMID 42700741doi:10.1016/j.ctarc.2026.101419 Journal ArticlepubmedProvenance
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PubMed
Retrieved
Sep 16, 2026
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normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260916-000001
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Pigment epithelium-derived factor (PEDF) is a potent endogenous immunomodulatory protein with anti-metastatic, anti-angiogenic, and anti-inflammatory properties, and has recently gained attention for its ability to target tumor cells across various cancers. However, the molecular mechanism…

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