Publication
Monomeric hapten dissociates FcεRI-evoked STIM1-Orai1 interaction and immediately terminates Ca2+ influx in rat basophilic leukemia cells.
Ruriko Suzuki, Rinka Ogawa, Tadahide Furuno
Biochemical and biophysical research communicationsOct 15, 2026PMID 42700582doi:10.1016/j.bbrc.2026.154539 Journal ArticlepubmedProvenance
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- Sep 30, 2026
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- ING-PUBMED-20260930-000001
Abstract
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Crosslinking of the high affinity IgE receptor (FcεRI) by multivalent antigen increases intracellular Ca2+ concentration ([Ca2+]i) through two sequential steps: (i) Ca2+ release from the endoplasmic reticulum (ER) and (ii) store-operated Ca2+ entry (SOCE) mediated by stromal interaction molecule 1…
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- cancerLeukemiadictionary0.60
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