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[⁶⁸Ga]Ga-CTR-FAPI versus [⁶⁸Ga]Ga-FAPI-04 PET/CT for patient evaluation in radioiodine-refractory differentiated thyroid cancer: A prospective comparative study.

Shengyan Liu, Xin Zhang, Ruochen Li, Ziren Kong, Xi-Yang Cui, Zhu Li, Cong Shi, Dongxiao Bian, Yihan Zhao, Qijun Li, Yijin Pan, Zhaohui Zhu, Zhibo Liu, Shaoyan Liu, Yansong Lin

European journal of nuclear medicine and molecular imagingSep 5, 2026PMID 42700251doi:10.1007/s00259-026-08150-4 Journal ArticlepubmedProvenance
Source
PubMed
Retrieved
Sep 17, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260917-000001
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OBJECTIVE: Incorporating a sulfur (VI)-fluoride exchange (SuFEx) chemistry-based linker, FAPI-based covalent targeted radioligand (CTR) showed better tumor binding affinity and longer retention time than FAPI-04 in animal studies. This study for the first time compared the lesion detection efficacy…

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