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Pentachlorophenol enhances bladder cancer cell invasion through altered protein stability.

Ranran Zhou, Wansong Zhang, Ming Xia, Ker Zhang, Wei Luo, Tianhang Zhu, Cheng Yang, Cundong Liu

iScienceSep 18, 2026PMID 42699065doi:10.1016/j.isci.2026.117357 PMC13543803Journal ArticlepubmedProvenance
Source
PubMed
Retrieved
Sep 26, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260926-000001
Published

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Pentachlorophenol (PCP) is a persistent environmental contaminant, but its effect on bladder cancer invasiveness is unclear. Here, we show that environmentally relevant PCP concentrations enhance invasion of T24 and SW780 bladder cancer cells, with limited effects on migration or proliferation.…

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