Publication
Photosensitive ropivacaine- and chlorin e6-loaded hydrogel targeting the substance P-tachykinin receptor 1-toll-like receptor 7 axis enhances photodynamic and photothermal therapy against oral cancer.
Yingbo Feng, Junbo Zhao, Mingming Zhang
Acta biomaterialiaSep 3, 2026PMID 42692233doi:10.1016/j.actbio.2026.09.003 Journal ArticlepubmedProvenance
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- PubMed
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- Sep 26, 2026
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- ING-PUBMED-20260926-000001
Abstract
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This study examines the important role of neuro-tumoral crosstalk in oral squamous cell carcinoma (OSCC) progression and therapy. We identified that dorsal root ganglia (DRG)-secreted substance P (SP) activates a pro-metastatic Tacr1-Tlr7 neuroinflammatory axis. To therapeutically disrupt this…
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- cancerMalignant Lip and Oral Cavity Neoplasmdictionary0.60
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