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KRAS Expression Complements Genomic Profiling in Identifying Therapeutic Vulnerability in Gastric Cancer.

Yu-Lun Chen, Wei-Ching Chen, Ta-Sen Yeh, Hsing-Hua Ho, Tse-Ching Chen, Wen-Ching Wang

Biomedical journalSep 3, 2026PMID 42692168doi:10.1016/j.bj.2026.101036 Journal ArticlepubmedProvenance
Source
PubMed
Retrieved
Sep 8, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260908-000003
Published

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BACKGROUND: Gastric cancer (GC) remains a major therapeutic challenge. Although alterations in the RAS pathway occur in over 50% of tumors, only a limited proportion are clinically actionable. We investigated whether KRAS expression complements genomic profiling for patient stratification and…

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