Publication
Fusion isoform multiplicity and impact on treatment outcomes in ALK-rearranged non-small cell lung cancer with next-generation tyrosine kinase inhibitors.
Damien Humbert, Adrien Buisson, Mathurine Basset, Anne-Claire Toffart, Luc Odier, Stéphane Hominal, Chloé Herreman, Sylvie Chabaud, Maurice Pérol, Anne Mc Leer, Aurélie Swalduz
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- PubMed
- Retrieved
- Sep 19, 2026
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- normalized (units and labels harmonized; values unchanged)
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- ING-PUBMED-20260919-000001
Abstract
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BACKGROUND: ALK-rearranged non-small cell lung cancer (NSCLC) reported controversies regarding the impact the ALK-fused genes on treatment outcome. Fusion isoforms are structural variants of the same fusion transcript. Recent evidence suggests that the presence of multiple isoforms within a single…
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- cancerMalignant Lung Neoplasmdictionary0.60
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