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Clinical outcomes and genomic features of uncommon EGFR exon 19 deletion subtypes in osimertinib-treated non-small cell lung cancer.

Hiroto Hatano, Tatsuya Yoshida, Ryoko Inaba Higashiyama, Masayuki Shirasawa, Yoshiro Nakahara, Katsuhiko Naoki, Hiroshi Nokihara, Kentaro Gosho, Yuji Uehara, Yukio Hosomi, Ayu Kiritani, Hiroshi Wakui, Yuki Shinno, Yusuke Okuma, Hidehito Horinouchi, Noboru Yamamoto, Yasushi Goto

Lung cancer (Amsterdam, Netherlands)Oct 1, 2026PMID 42691830doi:10.1016/j.lungcan.2026.109604 Journal ArticleMulticenter StudypubmedProvenance
Source
PubMed
Retrieved
Sep 29, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260929-000001
Published

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BACKGROUND: Epidermal growth factor receptor (EGFR) exon 19 deletion subtypes may be associated with differential survival outcomes following EGFR-tyrosine kinase inhibitor treatment. However, evidence remains scarce, particularly regarding osimertinib, and the underlying biological mechanisms are…

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