Publication
Cancer-associated fibroblasts-derived CAV1 promotes epithelial-mesenchymal transition and stemness in bladder cancer through activation of the LIF/STAT3 signaling pathway.
Qi Wang, Dengdian Wang, Haihong Jiang, Jie Min, Lin Hu, Jiatong Yin, Xiansheng Zhang
Translational oncologySep 3, 2026PMID 42691512doi:10.1016/j.tranon.2026.103001 Journal ArticlepubmedProvenance
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- PubMed
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- Sep 13, 2026
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- ING-PUBMED-20260913-000001
Abstract
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BACKGROUND: Cancer-associated fibroblasts (CAFs) are key components of the bladder cancer microenvironment, but how specific CAF subpopulations drive malignant progression remains unclear. This study aimed to identify CAF driver genes and elucidate the role of caveolin-1 (CAV1) in CAF-mediated…
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- cancerMalignant Bladder Neoplasmdictionary0.60
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