Publication
Characterization of acquired capecitabine resistance in MKN-45 gastric cancer cells reveals preserved apoptotic sensitivity.
Habibeh Sadat Mohseni, Shohreh Tavajohi, Abbas Kebriaeezadeh, Mohammad Hossein Ghahremani, Seyed Nasser Ostad
Daru : journal of Faculty of Pharmacy, Tehran University of Medical SciencesSep 3, 2026PMID 42690565doi:10.1007/s40199-026-00653-7 PMC13542033Journal ArticlepubmedProvenance
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- Sep 8, 2026
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- ING-PUBMED-20260908-000003
Abstract
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BACKGROUND: Capecitabine (Cap) is widely used in the treatment of advanced gastric cancer; however, the emergence of acquired resistance remains a major obstacle to its long-term efficacy. Although several gastric cancer models resistant to 5-fluorouracil (5-FU) have been reported, experimentally…
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- cancerMalignant Gastric Neoplasmdictionary0.60
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