Publication
Defactinib inhibits focal adhesion kinase to attenuate pancreatic cancer growth via PI3K/AKT pathway modulation.
Hui-Deng Long, Hao Wang, Wei Xiang, Tian-Yin Ma, Ting-Ting Du, Su-Feng Zhang, Fu-Xing Liu, Zi-Yu Chen, Cui-Ni Lu, Xin-Yun Liu, Xiao-Feng Wang, Tian Gong, Ning Han, Yue-Feng Cai, Chun Yang, Dong-Feng Chen, En-Yu Liu, Da Fu, Hong Yu, Wen-Guang Wu, Yu-Shui Ma
- Source
- PubMed
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-PUBMED-20260908-000003
Abstract
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Pancreatic cancer (PC) is a highly lethal malignancy characterized by aggressive progression and limited treatment options. Current standard-of-care treatments only confer marginal survival benefits, highlighting an urgent unmet clinical need to identify novel actionable targets and…
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Candidate 1
- cancerMalignant Pancreatic Neoplasmdictionary0.60
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