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IL20RB drives non-small cell lung cancer progression and immune evasion via K267‑dependent activation of JAK2 phosphorylation and STAT3 signaling.

Yanghao Wang, Guoyu Li, Weizhou Wang, Hengrui Zhang, Yu Zhang, Yajie Deng, Sirong Mu, Siyu Yuan, Yulin Tu, Jiayi Ni, Yongwen He, Li Bian

Lung cancer (Amsterdam, Netherlands)Oct 1, 2026PMID 42685527doi:10.1016/j.lungcan.2026.109599 Journal ArticlepubmedProvenance
Source
PubMed
Retrieved
Sep 29, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260929-000001
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INTRODUCTION: Tumor immune evasion is a pivotal mechanism driving therapeutic resistance and poor prognosis in lung cancer. The interleukin-20 receptor β subunit (IL20RB) is implicated in chronic inflammation and oncogenesis, but its precise function and molecular basis in non-small cell lung…

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