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Azacitidine-Venetoclax or Induction Chemotherapy for Acute Myeloid Leukemia.

Amir T Fathi, Alexander E Perl, Geoffrey G Fell, Brian A Jonas, Brittany K Ragon, Alice S Mims, Uma Borate, Gabriel N Mannis, Karen Quillen, Maximilian Stahl, Brandon J Aubrey, Paul Koller, Andrew S Artz, Monzr M Al Malki, Anthony S Stein, Guido Marcucci, Mary Linton B Peters, Timothy A Graubert, Peter Westervelt, Philip C Amrein, Hanno R Hock, Andrew M Brunner, Gabriela Hobbs, Rupa Narayan, Michelle H Lee, Peter G Miller, Alyssa L Watson, Richard Hao, Abigail C Marola, Jennifer Lombardi-Story, Shilton Dhaver, Michael R Grunwald, Yi-Bin Chen, Matthew J Weinstock, Andrew H Matthews, Ian McGovern, Brent L Wood, Christopher S Hourigan, Donna S Neuberg, Areej El-Jawahri, Ibrahim Aldoss

The New England journal of medicineSep 3, 2026PMID 42685316doi:10.1056/NEJMoa2602804 Journal ArticleMulticenter StudyRandomized Controlled TrialClinical Trial, Phase IIpubmedProvenance
Source
PubMed
Retrieved
Sep 15, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260915-000001
Published

Abstract

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BACKGROUND: Induction chemotherapy has long been a key component of curative therapy for fit patients with acute myeloid leukemia (AML), despite its frequently severe side effects and substantial health care utilization. For patients who are ineligible for induction chemotherapy, hypomethylating…

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Registered trialsNCT04801797

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