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Acute Myeloid Leukemia(AML) proteins for in silico drug design using pharmacophore modeling, molecular docking and molecular dynamics simulation.

Partho Bosu, Tonmoy Adhikary, Abu Sayed Rafi, Naveed Iqbal, Fatima Rasool, Payer Ahmed

PloS oneJan 1, 2026PMID 42685040doi:10.1371/journal.pone.0354456 PMC13537598Journal ArticlepubmedProvenance
Source
PubMed
Retrieved
Sep 14, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260914-000001
Published

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Acute Myeloid Leukemia (AML) is a hematological malignancy characterized by abnormal myeloid cell differentiation, disrupting normal hematopoiesis. This study utilized an integrated computational approach to identify key molecular targets and potential inhibitors for AML therapy. Analysis of the…

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