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Safety and Performance of the Colovac Anastomosis Protection Device. A Pooled Analysis of Prospective Studies Compared With Diverting Loop Ileostomy (SAFE-2025).

Patricia Sylla, Katherine Lam, Niels Komen, Jean-Jacques Tuech, Antonio Spinelli, Joseph Martz, Rebecca Rhee, Jorge Marcet, Guy Bernard Cadière, Philippe Rouanet, Aleksei Karachun, Quentin Denost, Narkhodzha Sametdinov, Andre D'Hoore, Sang Lee, Jérémie H Lefèvre

Annals of surgerySep 2, 2026PMID 42681563doi:10.1097/SLA.0000000000007171 Journal ArticlepubmedProvenance
Source
PubMed
Retrieved
Sep 14, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260914-000001
Published

Abstract

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OBJECTIVE: To compare the safety and effectiveness of the Colovac Anastomosis Protection Device with standard diverting ostomy (DO) following low anterior resection (LAR) for rectal cancer. SUMMARY BACKGROUND DATA: DO is standard of care (SOC) following LAR for rectal cancer but is associated with…

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Validated 4

Registered trialsNCT05010850NCT05180565NCT06152276NCT06540807

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