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Histological heterogeneity of SLFN11 expression and its association with response to carboplatin plus paclitaxel therapy in salivary gland cancer.

Satoshi Kano, Seijiro Hamada, Jun Taguchi, Nayuta Tsushima, Hiroshi Idogawa, Hayato Imanari, Masaki Kakumu, Mai Sakai, Yasushi Shimizu, Akihiro Homma

International journal of clinical oncologySep 1, 2026PMID 42681212doi:10.1007/s10147-026-03183-z Journal ArticlepubmedProvenance
Source
PubMed
Retrieved
Sep 30, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260930-000001
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BACKGROUND: Schlafen family member 11 (SLFN11) has emerged as a potential biomarker of sensitivity to DNA-damaging agents, including platinum compounds. However, its expression profile and clinical significance in salivary gland cancer (SGC) remain poorly understood. This study investigated the…

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