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Multifunctional nanoparticles for co-delivery of elacridar and paclitaxel for breast cancer local treatment.

Julia Sapienza Passos, Giovanna Cassone Salata, Giovanna Barros de Melo, Jessica Ribeiro Nunes, Alexandre A Steiner, João Agostinho Machado-Neto, Alyssa Panitch, Luciana B Lopes

International journal of pharmaceuticsOct 5, 2026PMID 42674320doi:10.1016/j.ijpharm.2026.127364 Journal ArticlepubmedProvenance
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PubMed
Retrieved
Sep 30, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260930-000001
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Breast cancer treatment is often limited by toxicity of systemic chemotherapy and by the development of drug resistance, which reduces the effectiveness of anticancer drugs. Delivering therapeutics directly into the mammary ducts has emerged as a promising strategy to increase drug concentrations…

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