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Water-exchange pharmacokinetic modeling improves DCE-MRI for ROI-based assessment of prostate lesions and of clinically significant prostate cancer.

Zejun Wang, Zhenjie Zang, Yong Li, Zhaoqin Huang, Hui Zhang, Qiang Fu, Ruiliang Bai

Magnetic resonance imagingDec 1, 2026PMID 42674229doi:10.1016/j.mri.2026.110778 Journal ArticleResearch Support, Non-U.S. Gov'tpubmedProvenance
Source
PubMed
Retrieved
Sep 29, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260929-000001
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PURPOSE: Quantitative multiparametric MRI (mpMRI) is increasingly explored for clinically significant prostate cancer (csPCa) detection; however, the diagnostic value of quantitative dynamic contrast-enhanced (DCE)-MRI in prostate cancer remains controversial. In this study, we aim to evaluate the…

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