Publication
Non-genetic remodeling drives leukemia propagation and reveals actionable vulnerabilities in acute myeloid leukemia.
Clement Larrue, Paolo Angelino, Sarah Mouche, Alexa S Green, Emeline Boet, Ismael Boussaid, Claudia Perez-Carretero, Rudy Birsen, Maxime Sajot, Thomas A Mckee, Ambrine Sahal, Nicolas Chapuis, François Vergez, Christian Recher, Véronique Mansat-De Mas, Olivier Kosmider, Pierre Sujobert, Frederic Catez, Jean-Jacques Diaz, Jean-Emmanuel Sarry, Petros Tsantoulis, Jerome Tamburini
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- PubMed
- Retrieved
- Sep 30, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-PUBMED-20260930-000001
Abstract
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Acute myeloid leukemia (AML) persistence and relapse are sustained by leukemia-propagating cells, yet the molecular programs supporting their expansion during disease evolution remain incompletely understood. Using serial patient-derived xenotransplantation, we establish a longitudinal model in…
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Candidate 1
- cancerLeukemiadictionary0.60
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