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Older adults with resectable gastric cancer undergoing perioperative chemotherapy or preoperative chemoradiotherapy plus perioperative chemotherapy: A secondary analysis of the AGITG TOPGEAR phase III trial.

Alexander Rühle, Alina Krause, Rachel L O'Connell, John Simes, Michael Michael, Bernard Mark Smithers, Rebecca K S Wong, Karin Haustermans, Nils H Nicolay, Trevor Leong, Florian Lordick

European journal of cancer (Oxford, England : 1990)Oct 5, 2026PMID 42673704doi:10.1016/j.ejca.2026.117005 Journal ArticleClinical Trial, Phase IIIRandomized Controlled TrialMulticenter StudypubmedProvenance
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PubMed
Retrieved
Sep 19, 2026
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normalized (units and labels harmonized; values unchanged)
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ING-PUBMED-20260919-000001
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PURPOSE: To evaluate treatment adherence, adverse events, and survival in older (≥70 years) adults undergoing perioperative treatment for gastric cancer. METHODS: Patients with resectable gastric/gastro-esophageal junction adenocarcinoma (ECOG 0-1) enrolled in the phase III TOPGEAR trial were…

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